It is with extreme personal sadness that I learned of the passing of John Brady this past weekend after a courageous battle with colon cancer. In 1987, John and I were in the same laboratory when our mentor George Khoury passed on. Since 1987, John has been an esteemed colleague and a thoughtful friend. He and I ran the annual NIH George Khoury Lecture, and I have always admired John’s insightul work on HTLV and HIV gene regulation. Our thoughts and prayers are with John’s wife Larrine and his children. John — you will be missed!!!