Below is the listing of the top 10 most highly read papers published in Retrovirology.  The access statistics represent direct downloads from the Retrovirology website during the 29 days in February.  The numbers do not account for additional downloads that may come directly from PubMed.

1. Accesses 1939	Research     Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy Pauline Chugh, Birgit Bradel-Tretheway, Carlos M.R. Monteiro-Filho, Vicente Planelles, Sanjay B Maggirwar, Stephen Dewhurst, Baek Kim Retrovirology2008, 5:11 ( 31 January 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]
2. Accesses 1126	Commentary     Hitting HIV where it hides Andrew I Dayton Retrovirology2008, 5:15 ( 1 February 2008 ) [Abstract][Full Text][PDF][PubMed][Related articles]
3. Accesses 981	Research     HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages Dinushka Dowling, Somayeh Nasr-Esfahani, Chun H Tan, Kate O’Brien, Jane L Howard, David A Jans, Damian FJ Purcell, C. Martin Stoltzfus, Secondo Sonza Retrovirology2008, 5:18 ( 4 February 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]
4. Accesses 863	Commentary     microRNAs in viral oncogenesis Vinod Scaria, Vaibhav Jadhav Retrovirology2007, 4:82 ( 24 November 2007 ) [Abstract][Full Text][PDF][PubMed][Related articles]
5. Accesses 812	Research     Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway Pablo N Fernandez Larrosa, Diego O Croci, Diego A Riva, Mariel Bibini, Renata Luzzi, Monica Saracco, Susana E Mersich, Gabriel A Rabinovich, Liliana Martinez Peralta Retrovirology2008, 5:19 ( 8 February 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]
6. Accesses 755	Commentary     RNA interference: a multifaceted innate antiviral defense Ajit Kumar Retrovirology2008, 5:17 ( 1 February 2008 ) [Abstract][Full Text][PDF][PubMed][Related articles]
7. Accesses 743	Review     Host-virus interaction: a new role for microRNAs Vinod Scaria, Manoj Hariharan, Souvik Maiti, Beena Pillai, Samir K Brahmachari Retrovirology2006, 3:68 ( 11 October 2006 ) [Abstract][Full Text][PDF][PubMed][Related articles][3 comments]
8. Accesses 550	Review     6th International Symposium on Retroviral Nucleocapsid Ben Berkhout, Robert Gorelick, Michael F Summers, Yves Mely, Jean-Luc Darlix Retrovirology2008, 5:21 ( 25 February 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]
9. Accesses 536	Research     Human T Lymphotropic Virus Type 1 protein tax reduces histone levels James M Bogenberger, Paul J Laybourn Retrovirology2008, 5:9 ( 31 January 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]
10. Accesses 471	Research     Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase Marleen CDG Huigen, Petronella M van Ham, Loek de Graaf, Ron M Kagan, Charles AB Boucher, Monique Nijhuis Retrovirology2008, 5:20 ( 13 February 2008 ) [Abstract][Provisional PDF][PubMed][Related articles]