Yearly Archives: 2016

Clinical trial management in a digital age

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Why do clinical trials still rely on paper-based data entry methods when there are so many technologies available to improve trial efficiency? New research published today in Trials provides a case study of integrating technology into trial design for a complex intervention and here, co-authors Cheney Drew and Vincent Poile discuss its impact on efficiency and what they see the future to hold for trial management.

Medical Evidence Medicine Technology

Does spinal manipulation of the neck cause strokes or is it just an “accident waiting to happen”?

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There is an argument on whether spinal manipulation carries enough benefits to justify the potential risk of causing a stroke and whether the manipulation itself is the cause of the stroke. To give us a background on this issue we invited Professor Charlotte Leboeuf-Yde to discuss two articles recently published in Chiropractic & Manual Therapies that fall on either side of this debate.

Medicine
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40 years of cancer evolution: time to understand its clinical implications

Tumor heterogeneity is observed at many levels: from cancer subclones in primary tumor with distinct characteristics to differences between primary and metastatic tumors in the same individual. As it affects treatment response, it is one of the key challenges in effective cancer management in the clinical practice. Here, co-authors of an article published today in BMC Medicine discuss their study of kidney cancer patients.

Medicine

Taking Control of Diabetes

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World Diabetes Day was set up to raise awareness of the health threats to people with diabetes mellitus. The theme this year is Eyes on Diabetes, focusing on the importance of screening for type 2 diabetes and screening for complications caused by all types of diabetes. To mark the occasion, ISRCTN looks at just some of the recent research to help prevent the development of diabetes and the complications of diabetes.

Health Medical Evidence Medicine

Update on Translational Oncology: different flavors of immunotherapy and cancer heterogeneity

Since its launch in July this year, BMC Medicine’s article collection on Translational Oncology article collection has attracted interesting research articles. Here, we present a brief overview of the most recent publications on adoptive immunotherapy for bladder cancer, tumor-associated macrophages in classical Hodgkin lymphoma, correlating tumor mutation load with immunotherapy outcomes and spatial transcriptome analysis of glioblastoma.

Medicine