Monthly Archives: August 2013

Can SSRIs provide a new treatment for bone loss?

    Guest blog post by Dr Carlo Galli, author of a timely Commentary published in Journal of Negative Results in BioMedicine, which discusses the debate surrounding seratonin in the treatment of bone loss in periodontitis. He argues that although contradictory, recent findings may lead the way to novel treatment opportunities for periodontitis and similar bone loss. One of the crucial aspects… Read more »

‘Tau-based therapeutic strategies’ – special series call for submissions

Alzheimer’s Research & Therapy is accepting research submissions for consideration in a special series on tau-based therapeutic strategies for Alzheimer’s disease and related dementias. There is great interest in finding therapeutics to reverse or remove tau aggregates from the human brain. Pathological aggregation of tau protein is associated with many neurodegenerative diseases, termed ‘tauopathies’, the… Read more »

Infectious Agents & Cancer announces new section on cancer centers in low- and middle-income countries

As low- and middle- income countries (LMICs) continue to face health challenges from infectious disease, they are concurrently challenged by the rising burden of non-communicable diseases including cancer. The International Agency for Research on Cancer (IARC) estimates that by 2030, the annual number of new cancer cases worldwide will exceed 21 million and the number… Read more »

A Call to Action from AllTrials

“Industry and academics must share all trial results: without this information, doctors are misled, and patients are harmed.” That’s Ben Goldacre summing up the motivation behind the campaign AllTrials, and yes, it’s just that simple. Launched in January 2013, AllTrials is an initiative on behalf of Sense about Science, Bad Science, the BMJ, and others… Read more »

MitoQ: a potential new therapy for inflammatory bowel disease?

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gut that causes pain and diarrhea. The most common forms of IBD are Crohn’s disease and ulcerative colitis. In the majority of patients these conditions can be well-controlled with medication, but surgery is sometimes required if treatment is not effective. Given the rising incidence… Read more »

Latest developments in Alzheimer's drug discovery

Accelerating the development of innovative treatments for Alzheimer’s disease and related dementias is the target for scientists brought together at the 14th International Conference on Alzheimer’s Drug Discovery, and the focus of a special thematic series in Alzheimer’s Research & Therapy. Hosted by the Alzheimer’s Drug Discovery Foundation (ADDF), on 9 – 10 September 2013… Read more »