Monthly Archives: December 2020
The impact of mass drug administration on Schistosoma haematobium infection: what is required to achieve morbidity control and elimination?
Using an individual based stochastic model and data from two different age-intensity profiles of infection prevalence and intensity, we explore the effect of mass drug treatment (MDA) on S. haematobium and examine whether we can achieve the WHO goals of morbidity control and elimination as a public health problem by using the current guidelines.
Over the past decades, viruses transmitted by ticks and mosquitoes have expanded their distribution and caused an increasing number of human outbreaks. Spatial modelling of ecological risk factors for virus circulation can help identify areas of potential emergence.
Researchers from the UK and Senegal assessed the reliability of facial cleanliness indicators used to measure a key component of the “SAFE” trachoma elimination strategy. The results presented highlights the need for further research into a reliable marker for face washing to guide trachoma and WASH campaigns.
Investigating the importance of the Schistosome digestive tract in host immune evasion, parasite survival and novel vaccine development
An investigation into schistosome digestive tract development reveals that the oesophageal gland, a site of protein secretion and entrance to the gut, could be a key organ for host immune system evasion and a site of substantial host-parasite interactions. New vaccine candidates on the horizon?