Monthly Archives: March 2012

Open science versus commercialization: an Open Debate in Genome Medicine

In the first Open Debate published in Genome Medicine, Timothy Caulfield and colleagues investigate the potential conflict between open science and commercialization policies in genomics research. Tackling an issue that’s fraught with controversy, the authors discuss the inconsistencies in messages aimed towards promoting openness or commercialization of science, and offer a solution for integrating both… Read more »

Medicine

Muscle wasting disease improved by Fasudil

Motor neurons are assembled and maintained by the SMN protein, but a genetic defect in the SMN1 gene can lead to spinal muscular atrophy (SMA), an incurable and inheritable disease which progresses during the lifetime of the patient. The disease affects adults as well as children, and is the most common genetic cause of infant… Read more »

Medicine

Special series 'The new FTD mutation on chromosome 9' – Alzheimer’s Research & Therapy call-for-papers

Alzheimer’s Research & Therapy is now accepting research papers for consideration in a special series for 2012 on the new FTD mutation on chromosome 9, guest edited by Professor Bruce Miller (University of California, San Francisco). This series will discuss new advances in frontotemporal dementia (FTD) with amyotrophic lateral sclerosis (ALS) related to mutations in C9orf72…. Read more »

Medicine
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Low back pain: rest versus exercise therapy

Low back pain is a short-lived common disorder but this chronic condition can last for up to 12 months in some patients. Although current clinical guidelines recommend exercise therapy, this is not usually encouraged for patients suffering from low back pain who also show pathological alterations to the bone and spine (Modic changes). It has… Read more »

Medicine