Monthly Archives: January 2014

The RBPome: unlocking a new layer in gene regulation

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In 2012, Genome Biology joined with a number of other journals to publish articles describing the ENCODE project, which set out to catalog how proteins bind to the genome in order to regulate transcription. With a similar goal, we published a special issue focused on epigenomics, which looked at both DNA-bound proteins and epigenetic modifications… Read more »

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Sweetening woody biomass

Aspen

The cell walls in wood, with their abundant lignocellulose, are a vast source of renewable biomass. To make this woody biomass a usable source, however, these raw materials require conversion into simple sugars, and then further processing by microorganisms into ethanol and other bioproducts. The major limiting factor for this process is resistance to the… Read more »

Proceedings from the 39th Indian Society of Human Genetics conference

Kalam-Liehr – blog pic

The proceedings from the International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics have been published as a supplement in Molecular Cytogenetics. The meeting took place on the 22-25 January, 2014, in Ahmedabad, India. Former President of India, Dr A. P. J. Abdul Kalam, inaugurated the conference, and… Read more »

Sigma factor networking and bacterial versatility

False colour E. coli

In the bacterial RNA polymerase transcription complex, the sigma factors play the role of guide, specifying where in the genome the complex binds – and thereby which genes are turned on at any one time. Lab favourite E. coli has seven such sigma factors, one of which has a ‘housekeeping’ role in standard conditions, with… Read more »

Cancer progression Genome Biology special issue: call for papers

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Genome Biology would like to announce that we are now inviting Research, Method or Software manuscript submissions for publication in a special issue on cancer progression and heterogeneity, which is planned for late summer 2014. Recent advances, such as single-cell sequencing technologies, are allowing us to study cancer genomics at a depth that was not… Read more »

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Welcoming Monique Nijhuis to the Associate Editorial team

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Retrovirology is delighted to welcome a new Associate Editor to the team, Dr Monique Nijhuis, associate Professor of Virology at the University Medical Center Utrecht in The Netherlands. Dr Nijhuis’s laboratory works on antiviral escape and focuses on HIV and viral hepatitis. Dr Nijhuis’ contribution as a member of the scientific committee for the Frontiers of Retrovirology meeting… Read more »

One to three men fathered most western Europeans

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A recent study published in Investigative Genetics has shown that the genetic lineage of most Western Europeans started from just one to three men, sparking many and varied online discussions. The study, led by Chris Tyler-Smith, involved producing a model to investigate the expansion of Neolithic genetic lineages throughout Africa and Europe. Both Africa and… Read more »