Monthly Archives: February 2019

Seeking and sourcing safe, fast acting macrofilaricides


An international consortium of scientists, the anti-Wolbachia consortium (A∙WOL), aimed to discover novel treatments for filarial diseases by targeting the parasite’s endosymbiotic bacterium, Wolbachia. Through collaboration with a global pharmaceutical company (AstraZeneca), they achieved the first ever industrial scale high-throughput drug discovery screen for filariasis. This resulted in the identification of five novel, fast acting compounds.

Biology Developing World Health Medicine