Scientific uncertainty not mirrored in clinical practice
A pilot study of the contraindicated use of metformin in diabetic patients with heart failure published last week in Trials has highlighted a potential… Read more »
Latest posts by Iain Hrynaszkiewicz (see all)
- Fishy fossils and lemur survival: case studies in data curation - 1st September 2017
- Promoting research data sharing at Springer Nature - 5th July 2016
- ‘Availability of supporting data’: crediting transparency and enhancing the literature - 7th July 2011
The challenge of conducting surgical trials
The randomised controlled trial (RCT) has been described as the ‘gold standard’ study design for assessing new healthcare interventions. But… Read more »
Alzheimer’s Research & Therapy: now accepting submissions
Alzheimer’s Research & Therapy, a new journal published by BioMed Central, is now accepting submissions. Alzheimer’s Research & Therapy aims to be… Read more »
More guidance needed to prevent outcome reporting bias
A review of reporting guidelines for randomized controlled trials (RCTs), conducted by Dwan et al. and published in Trials has highlighted the need for more… Read more »
Trials accepted for MEDLINE indexing
Following a review by the Literature Selection Technical Review Committee, Trials has been accepted for indexing in MEDLINE, the National Library of… Read more »
Declaration of Helsinki calls for mandatory registration of clinical trials
The World Medical Association revised the Declaration of Helsinki on 18 October 2008 at its General Assembly in Seoul, South Korea. The new version replaces all… Read more »
Part 1 of Arthritis Research & Therapy's 10th anniversary issue published
To mark its 10th anniversary, Arthritis Research & Therapy is publishing a comprehensive collection of review articles, entitled “The Scientific Basis of… Read more »
Trialists should describe how they deal with missing data
A review of randomized controlled trials (RCTs) in four leading medical journals has revealed that the majority of studies did not use imputation to deal with… Read more »
Warnings against Influenza pandemic
In new evidence presented to a House of Lords committee in July, the UK government has warned that 50 million people could die as a result of failing to act… Read more »
Study highlights inadequate data monitoring in clinical trials
In a recently published research article in Trials, Dr Floriani and colleagues assess the prevalence of interim analyses in 150 cancer randomized controlled… Read more »