Charles Auffray is the President of the European Institute for Systems Biology Medicine based in France (EISBM - www.eisbm.org). At EISBM, Charles Auffray is fostering the transition from reactive to proactive Systems P4 Medicine through the Pioneers of Health and Wellness Project in partnership with the Institute for Systems Biology in Seattle, and a worldwide network of systems medicine centres, including the Luxembourg, New Delhi and Shanghai Centres for Systems Biomedicine, working toward a World Alliance of Health and Wellness. All are joining forces to form a global coalition for deep phenotyping of COVID-19 patients.