The First International Pediatric Cardio-Oncology Meeting was held on October 21-22, 2022 in Cincinnati, OH. A number of original research scientific abstracts were received following an international call for submissions for cutting edge cardio-oncology research. All abstract submissions were critically reviewed by members of the conference’s organizing committee. Four submitted abstracts received the highest scores for significant scientific contributions to this field. These four were presented from the platform at the meeting as oral presentations and were awarded the “Cardio-Oncology Journal Prize” for top original research posters. Here, the winners provide details on their research.