Monthly Archives: July 2014

From Shell shock to PTSD – a century of military psychology

1st_Lt._Keller_Fires_M16_(7637605542) (1)

In the history of medicine, it’s a rather morbid fact that war often leads to great medical breakthroughs – as the weapons of war change, doctors must innovate in order to meet these new challenges. When the First World War started 100 years ago today, the British Expeditionary Force (BEF) setting out for France envisaged… Read more »

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Hepatitis E-A virus with two faces

Hep E-the 2 faces

The fierce heat of the sun was burning. Aba wiped the sweat from her brow as she trudged through the farm entrance and emptied the cocoa beans into the designated crate. Hot and parched from carrying the heavy load. She knelt by a small cloudy pond. Not fussed by its murky appearance she cradled her… Read more »

Mood disorders: Exploring the placebo effect, improving treatment and the promise of pharmacogenetics

Antidepressant drugs which alleviate symptoms of depression have received much attention in the news recently, showing that the UK is the 7th highest country in the West to prescribe the drugs. The astounding rise in NHS spending on these pharmacological agents is suggested to be due to “medicalization” of normal sadness. Selective serotonin reuptake inhibitors… Read more »

“You like to-may-to, I like to-mah-to”…what’s the problem with studying the Mediterranean diet?

Wholegrain (Kaldari)

The Mediterranean diet has been linked to many health benefits, from improved longevity to reduced incidence of cardiovascular disease, cancer and depression. However, while the positive impact of this dietary pattern is well-documented (see our previous blog), a number of unanswered questions and unresolved controversies remain. As editors at BMC Medicine, we have encountered differences… Read more »

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The global fight against TB: identifying childhood infection and diagnosing complications

TB x-ray (Jmh649)

Recent estimates suggest that childhood tuberculosis (TB) rates are much higher than previously reported. The predictions, carried out by researchers at the University of Sheffield, Imperial College London and the Global Alliance for TB Drug Development, took bacterial behavior and adult infection rates into account across 22 countries with the highest incidence of TB, and… Read more »

Polio eradication – the race continues…

Polio child

In May 2014, the World Health Organisation declared the rapidly increasing spread of polio an international public health emergency. The virus, which usually affects children under five years old, is typically spread through faeces contaminated drinking water, causing irreversible paralysis and death in the most severe cases, where respiratory muscles are immobilised. Polio is currently… Read more »

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Where’s the evidence for how we run clinical trials?

trial forge

No one ever said that doing a clinical trial was easy. Indeed it often feels like a Sisyphean task, when faced with obdurate funding committees, or centres that seem unable to recruit a single patient, when just six months previously they were inundated with them. Every piece of research has its pain points; however, sometimes… Read more »

The Evidence-Based Medicine renaissance: holy grail or poisoned chalice?

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Today at our Health Services Research Conference, Professor Trish Greenhalgh announced her new campaign for Real Evidence-Based Medicine. In this guest post, her fellow campaigner Dr Jeremy Howick writes about why we need a renaissance in Evidence-Based Medicine. A meeting involving critics and proponents of Evidence-Based Medicine (EBM) took place in September 2013 to discuss… Read more »

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