Monthly Archives: February 2013

This week in BMC Medicine: DNA and diagnostics – how epigenetics and clinical biomarkers can influence healthcare

BMC Medicine recently published research showing that nicotine exposure during pregnancy in rats induces asthma in their offspring via epigenetic changes in germ cells. Importantly, the authors showed that these changes can affect two generations of offspring, thereby concluding that a grandmother’s smoking habits can lead to an increased risk of asthma in her grandchildren…. Read more »

From neuroscience to neuro-rehabilitation

Over the last few decades, our understanding of the pathophysiology of Central Nervous System (CNS) disorders has increased. This has paved the way for research into possible therapeutic approaches for treating CNS disorders, such as spinal cord injury and hemiparesis following stroke, in order to improve the quality of patients’ lives. Yet whilst research in… Read more »

Where is lupus therapy going?

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with heterogeneity in clinical manifestations and disease course, characterized by numerous antibodies and organ damage.  The disease has been the focus of many basic and clinical investigators and has stimulated great interest in the pharmaceutical community to develop new treatment targets. An Arthritis Research & Therapy… Read more »