Science works best when it’s open and transparent. Researchers and journal publishers are increasingly encouraged to drive forward initiatives to improve the transparency and reproducibility of scientific results. This is particularly true in the case of how best to report the findings of clinical trials. These large studies often have direct public health implications…. Read more »
We are pleased to announce that 15 more titles from BioMed Central’s portfolio of journals have recently been accepted for Impact Factor tracking by Thomson Reuters and should receive their first Impact Factors in June 2013. The acceptance of these titles for tracking reflects their growing prominence and reputation in their respective fields. This is… Read more »
Around 150 million people worldwide are chronically infected with hepatitis C virus (HCV), and around a quarter of those infected develop liver cirrhosis. Treatment for HCV is only effective in some patients, and it is important to take a patient’s genotype into consideration to decide which treatment should be given. A meta-analysis by Maria A… Read more »
Millions of people around the world suffer from neurodegenerative conditions such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis and Huntington’s disease. Neurodegenerative diseases primarily affect an older population, and as we continue to live longer, incidences of these are expected to soar. Finding treatments and cures for neurodegenerative diseases is therefore a… Read more »
In September 2009, Journal of Translational Medicine (JTM) and the then International Society for the Biological Therapy of Cancer (iSBTc) launched the Tumor Immunology and Biological Cancer Therapy section in the journal and with it JTM became a venue for the discussion of hot issues in tumor immunology which were highly relevant to translating novel… Read more »
To celebrate the launch of Cases Database, BioMed Central is offering a discounted article processing charge to Journal of Medical Case Reports authors, and expanding the scope of its Case Report of the Year Award. Creating Cases Database, BioMed Central’s freely accessible database of peer-reviewed case reports which launched last month, was one of the… Read more »
The Human Leukocyte Antigen (HLA) is the most polymorphic region of the genome, with a key role in the immunological response. In humans, HLA genes are contained within the major histocompatibility complex (MHC) locus, consisting ofmore than 200 genes located on chromosome 6. Determining individual HLA types is of critical importance in many aspects of… Read more »
Cystic fibrosis is a rare but lethal autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR is responsible for the balance of salt versus water movement in cells, and defects in CFTR lead to thickened secretions, for example in the lungs, which cause recurrent lung infections that eventually… Read more »