The latest research in the pseudoenzyme field was presented at what claimed to be the world’s first dedicated pseudoenzyme conference in Liverpool earlier this month, with the ways in which they function and evolve among the topics discussed.
Disgusted with current peer review processes, some are opting out of peer review altogether and publishing on preprint servers. Can we offer a less radical solution?
Being rooted in place plants have to change shape to adapt to their environment. Understanding this plasticity provides us the tools to guide plant development in a changing world.
To mark Jeans for Genes Day in the UK, Sam Rose discusses current research on genetic diseases and where charity funds are being distributed.
Peer reviewers are the unsung heroes of science. We celebrate reviewers through a series of interviews with people who have made particularly strong recent contributions to Genome Biology as reviewers. The first interview is with Hyongbum (Henry) Kim, an Associate Professor at Yonsei University College of Medicine in South Korea.
A new article in Veterinary Research reports on the first case of chronic wasting disease in Europe. Chronic wasting disease (CWD) is a prion disease affecting reindeers and other cervids, and up until now has only been seen in North America. Dr Christina Sigurdson, a specialist in the field, talks here prion diseases and the implications of this finding.
The genetic diversity of muscle diseases is extensive, and new tools are required to investigate the mechanisms of disease and test new therapeutic interventions. Cells isolated from patients serve as a source for specific models that allow for the study of disease in the context of the patient’s own genetic landscape, and these cellular models are taking on increasing importance.
In the light of increasing knowledge on the role epigenetic factors play in disease, it is now becoming apparent that epigenetics could be ideal therapeutic targets – particularly taking into consideration that many of these epigenetic factors are reversible. Epigenetic drugs are incredibly potent and can help reverse abnormal gene expression that can result in various diseases.
New research published in Molecular Neurodegeneration reports on the development of effective immunotherapies for tauopathies, with some surprising results. Here, Erin Congdon and Einar Sigurdsson discuss their research.