Tackling ischemia to treat DMD
In a recent publication Nelson et al proposed to use PDE5 inhibitors to treat DMD. Duchenne Muscular Dystrophy (DMD) is a fatal progressive disease that affects… Read more »
In a recent publication Nelson et al proposed to use PDE5 inhibitors to treat DMD. Duchenne Muscular Dystrophy (DMD) is a fatal progressive disease that affects… Read more »
Two recent reports by Cortes et al. and Lieberman et al. reveal a novel role of skeletal muscle on SBMA pathology and opens new avenues for alternative… Read more »
Under normal conditions skeletal muscle satellite cells (muSCs) are in a quiescent state, but when stimulated by damage, they re-enter the cell cycle to… Read more »
Much of what we know about the cardiac Ryanodine receptor (RyR2) relates to its role in excitation-contraction (EC) coupling. During this process, cell membrane… Read more »