New research published in Respiratory Research discusses the importance of systemic inflammation in the pathogenesis of COPD and provides proof-of-principle that cellular diagnostics in stable COPD is able to identify at least two systemic inflammatory processes. In this blog, author of the research Prof. Leo Koenderman tells us more.
As more and more light is being shed upon the molecular landscape of cancer, the architecture for both genetic and epigenetic changes is being exposed. Epigenomic changes are associated with modifications in gene expression at a post-transcriptional level without any alterations to the genetic code itself. In this genome-wide epigenetic study, published in BMC Medicine, we provide a comprehensive overview of the disrupted methylation patterns that occur during the development and progression of cutaneous melanoma.
Copaxone is a drug used to treat multiple sclerosis (MS). It is thought that genetics may account for the variability in patients’ responses to the drug. Research published today in Genome Medicine investigates the association between responses to Copaxone and single nucleotide polymorphisms located in genes across the genomes of MS patients.
Heart disease touches everyone at some point in their lives. Both sufferers and their loved ones struggle to deal with the huge impact it has on their lives. Wear it. Beat it. is an initiative led by the British Heart Foundation which asks the nation to wear red to raise money to help fight heart disease. To get in on the action and help raise awareness, ISRCTN spoke to Sarah Payne Riches, a doctoral student at the University of Oxford, about her BHF funded study, “SALT-SWAP”, which was recently registered in the ISRCTN Registry.