March is an important month for raising awareness of primary headache disorders and the research being done to understand and treat them, with Brain Awareness Week 11^th – 17^th and Cluster Headache Awareness Day on the 21^st. To coincide with these important events we invited Anne-Sophie Wattiez and Doga Vuralli to talk about their recent review in The Journal of Headache and Pain which explores how we can use animal models to better understand the pathophysiology of headache disorders and develop potential treatments.