Monthly Archives: November 2018

Challenges to globalizing genetic predictions of health and disease


Genome-wide association studies (GWAS) have given us unprecedented insight into heritable traits and diseases. However, because the vast majority of studies have used European cohorts, the results of GWAS paint a biased picture and cannot always be generalized to other populations. Research published today in Genome Biology explores these biases, finding that genetic predictions of disease risks can be grossly misestimated.

Biology Health