With the abundance of new findings on the effects of various foods on our health, how shall we select the best quality evidence and recommendations to follow? Here, we summarize recent studies published in BMC Medicine, which provide evidence on the effects of various nutritional modifications on health outcomes.
Monthly Archives: March 2017
New research published today in BMC Medicine evaluates the clinical performance of a new male infertility test, based on the detection of TEX101 protein, that could help to eliminate the need for invasive diagnostic biopsies. Here author of the study, Andrei Drabovich, tells us more about this test and the function of TEX101 protein.
March is blood clot awareness month and the theme for this year is “Know More, Share More”. So to aid in the sharing of knowledge on blood clots and strokes we invited associate editor of Thrombosis Journal, Bob Siegerink, to tell us about updating Virchow’s triad for thrombotic diseases and the importance of communication between stroke and thrombosis researchers.
Over the past few decades the concept and application of self management of asthma have evolved, reducing both emergency service use and the day to day symptoms of asthma. In this blog, authors of a new review in BMC Medicine, talk us through the history of self management and the positive evidence supporting it.
Building on the work of a study published last year with an accompanying blog by Carl Heneghan, a new article published in Trials explores how marketing undermines clinical trials. Here, the author of the paper, Alastair Matheson, discusses what defines a marketing trial, reframes companies as authors and asks what can be done to combat this issue.
The brain is one of the most complex organs in the human body, controlling everything from the way we think and behave to how we move. Brain injury can have far-reaching consequences, but around the world millions of researchers are working to stop it in its tracks. In support of Brain Awareness Week (BAW), the ISRCTN registry is taking a look at some of the latest clinical trials making headway on limiting the damage of brain damage.1
Attention disorders are prevalent in 5% of the total population and are commonly diagnosed on the basis of a patient’s clinical history and an examination aided by symptom check sheets. A new study published in BMC Medicine finds that EEGs (electroencephalograms) can reliably detect specific brain differences associated with attentional disorders that are not observed in control subjects. Here to tell us more is lead author of the study, Frank Duffy.
A large epigenome-wide association study published today in BMC Medicine provides the evidence that childhood obesity is triggered by specific factors occurring before birth, such as mother’s lifestyle, and fetal genetic and epigenetic characteristics. Here, author Neerja Karnani summarizes these findings.1
The need for child-centric reporting guides for pediatric clinical trial and systematic review protocols and reports
Systematic reviews (SRs) and meta-analyses (MAs) of clinical trial results are regarded as the highest level of medical evidence to establish the effectiveness and safety of interventions in a comprehensive, transparent, and reproducible nature. Unfortunately, evidence shows that not all SRs and trials are guaranteed to have been performed with the necessary methodological rigor. A study published today in Systematic Reviews reports on evidence of incomplete child-centric reporting details. Here the authors tell us more.