Genome Medicine visits HUPO 2011: It’s all speeding up

There can’t
be many ‘omics’ researchers in the past year who haven’t heard conference
speakers question when – or whether – genomic medicine is going to make an impression
on the clinic. The human proteome organization’s recent conference in Geneva (HUPO
2011
) was no exception, but there were clinical successes to celebrate and a consensus
appears to be emerging on how to improve the hunt for useful biomarkers.

Via Wikimedia Commons, credit Janice Haney Carr, Centers for Disease Control and PreventionLet’s look at the achievements. The first is the introduction of mass spectroscopy
to hospital microbiology labs. 
MALDI-TOF mass spectroscopy is now used in 300 clinics to diagnose bacterial and
fungal infections. This is resulting in a faster diagnosis at a cheaper price
than for standard biochemical tests currently used. The increased speed allows doctors
to prescribe specific treatments more quickly. The aim is to provide a
diagnosis within a couple of hours of arriving at a hospital; numerous
approaches to avoid overnight culture are being investigated, and this should
remove the remaining bottleneck.

The second clear achievement from HUPO is the improvement in
proteomics technology. The close collaboration with industry is paying off, and
the number of research posters presented from industry illustrates the rapid
developments taking place. 

Talk after talk referred to the discrepancy between the
number of biomarkers ‘discovered’ (150,000) and the number of biomarkers being
used in the clinic (100). But the HUPO community seem to be responding by establishing
biomarker pipelines – a clear theme of the meeting.

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AlNQ3BZuD9pxuIpucLVI9iyrBlbHYLCAPWPieyF5vJHfQSdFqIU0B1I+vDTFW8SMzY0BDHG/dhM4rhpxofIk0N+On6auc7426SFLGijBJ1EYRqGOaDZedkOJBpoVpTarPrSB/QffITUsn/qmohBQ4PkVQbpNFRpJDFeaWRJ7Zv5z1GuyE+hIAFlAmqEELagEIHCJArR0EgtIDz6PMMQGmos0BigU9AYvOZqUIJOQYWFAYfo/+e0TUNQrklsJvFPck1g/N3jcoUKhQbkmuE3QQPX4QiU2gkSZsQQUdb0bp4wsqD4MbkOtQ1N/Ukz1j8g17Uj2LIxhVudSGUGnoZh0I/1UMMV42mEaKGLAoYTBT/8dNmb5LT1jQGMcczECZw0zQTGyaEza8X4l3JtpwTDiqIUDDNAs/EyNyhXKzIopKf7/KePVKMeqANhCoYJXqeRQUGVQjLjlT8srR2RkesfQ0auw5eMXF9ZMnJNewRpIiPXoUNGrsOXjFxfWTJyTXsEaSIj16FDRq7Dl4xcX1kyck17BGkiI9ehQ0auw5eMXF9ZMnJNewRpIiPXoUNGrsOXjFxfWTJyTXsEaSIj16FDRq7Dl4xcX1kyck17BGkiI9ehQ0auw5eMXF9ZMnJNewRpIiPXoUNGrsOXjFxfWTJyTXsEaSIj16FDRq7Dl4xcX1kyck17BGkiI9ehw8ssV9M0k78m1xoOqhm5Pp2MXF9ZMnJNewRpIiPXocPLKlcTJ/GAZeMYJzD+7kEvNxm8xZbSJXUc0CnYRYJQ2k/vkCYj11eWjFzTHkGayMh16PASy9XEGbn+R2Tk+sqSkWvaI0gTGbkOHTJyHb5k5PrKkpFr2iNIExm5Dh0ych2+ZOT6ypKRa9ojSBMZuQ4dMnIdvmTk+sqSkWvaI0gTGbkOHTJyHb5k5PrKkpFr2iNIExm5Dh0ych2+ZOT6ypKRa9ojSBMZuQ4dMnIdvmTk+sqSkWvaI0gTGbkOHTJyHb5k5PrKkpFr2iNIExm5Dh0ych2+ZOT6ypKRa9ojSBMZuQ4dMnIdvmTk+sqSkWvaI0gTGbkOHTJyHb5k5PrKkpFr2iNIExm5Dh0ych2+vLRyNZOxBMb9GE8FA3K1CyoNVQrqJDJIlO4Tm34yck17BGkiI9ehQ0auw5eXVq44EUuaOI7xtCflSg7Kddj7NSPXtEeQJjJyHTpk5Dp8ycj1lSUj17RHkCYych06ZOQ6fMnI9ZUlI9e0R5AmMnIdOmTkOnzJyPWVJSPXtEeQJjJyHTpk5Dp8ycj1lSUj17RHkCYych06ZOQ6fMnI9ZUlI9e0R5AmMnIdOmTkOnzJyPWVJSPXtEeQJjJyHTpk5Dp8ycj1lSUj17RHkCYych06ZOQ6fMnI9ZUlI9e0R5AmMnIdOmTkOnzJyPWVJSPXtEeQJv5gudJPytX6YuWq/yv8/LtIqJFQI5/+eo2CGjlwNh+VUy9QKahQSKWgQUGdgurvv+GMXH+RwrMkm+4m9FzIyHUo8lxq16ss17//JNfIz+RKIMOKQhQyKKhRUH2MNEb5x3YXf5hc32Dmvv3RUhL5KRQkoUxCjRLCJAxRMEzBEAUNCmoUUigkk4JEIYlGwSeRaCjTUKGQQgnBAZA8+O41Cmo0VGmopl5GA50G4d+HhGESRigYpkCYAQbDGwxv0CBMwohFiGYJ0TFCNEuIZAthawoUsaKIFYWtKGxFulXQCEEhBYkQDMrbSSLZyvtYUbd79zJ8t9Uls16fbX5HtqclyxOiQJSDARsIsEBmgMYAnQYpg2ok0qyCahUkUpAZoL58csVmEpummUziZBybCYy/e9jLfc6/xZXQJbUc1CjUSYLwU8c3DFBZoDJAS2VHgQgFohSI0iBKgyjLR1k+SoEoCaMkjJAwFV+IRDqJdBJpJFIfkaYG/B+3w5dQrkkzFsc4hvHUwQf3Ox57cH/q0/3kVzTQQhkos6n/AomFQRbIqUf804/VBxroNNQYoDFQYYHMApmGKgNSDy7WfjbAGvwnhYYDZ5JEGol0YqB66CR69NtVGugUDD3+7QM1R1BIpBKCTCKVRAYJwyQySGiQ0CDRo5qWqmzPPmh4NeWqRA++ZZ32zwkLbJ42WtCtKEwIYQpqqVhJpFqFkBWlGq9BQ4kWfLTgo5GfRqnOOZXvozSfAv0LfpoFIZ0c6C1TcWtPBqRTMJTqTGgQSVWqx1qcQgryIwghSApBEqmPZf3rPJOn/yC5BjpfZ+a++aRcaRQmwc/kqpKCTApBCgVp5KeRn4F+FvpZGGBQkIYyDVUaKpTgo4R2SvBRKEg92ZPSUKXQM8o1RMIICVOrGSGON1KwfIgC0WwhOlrsHC12jxajWaJhEcIWIWJB0RRWFBk0a5AU/FbBIL17CaRm822cV3cIB+3wIAeNLPcusnIXWdluhXsYtNcGfHbgswOJBRrLh2gQplKtF2kWQbF4g4QoMUBlgPESyjVpmokkTjwmV89bXDFdUs1BhUJREoSf2sswUGGhzABloO8DUQp0pqD5TpbvZPlOiu8iYRcJO0nYScLooF+NweakkoJMIiX9shxOcn3qX8V5Uq4KA2UWSiwMciDIwQAH/RyQmJ/kOlAfaGCwQGOBxgGFAzIHZBbKLFAGu+NHNUenoMYAlYXK4Ph7QK4E0q3IIJCR6nOpR+PvgW4n/OjbByuPYhUUqyATgkrCyGNjuPCAaAfIyBWr0YPvWKa+N2G+Y1CuViFMIo2GCg0VAukWIWxFXTTfTYMQDSVaaKOFVlpop5FMA4MG4X9froMzk4F+cjAgKzKsgk4IP5NriIJhCkQp0EXzXTQwHpNrai4nk0KQFIKEGLSKfkIMDAytfpeXU66pcQHSaKgyUOaAZAOSDcgcr7JAY6BBA4NGAVpop5GPRkEaphZdH/2cEIEMEqlkagCbWoj49YJGQ40BOgdUu+cxeI0BOgl1ixDKFkMWMZWWTiIjNc8mYYhCBoUUCgVTmieRQQj7SSFMwCCDDMazl6rY4xAjlNBAVe2m5nWMdkdotJ8FEgdkFqgsMBg+QoMoBSIkChFItwqKVXypZ67PQa4UVCgUoF
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