A special series of companion papers from the FANTOM4 consortium

Fantom4
Genome Biology and BMC
Bioinformatics
have published the first articles in a new
cross-journal article series
reporting results from FANTOM4,
the latest research project from the FANTOM consortium.

FANTOM (Functional Annotation of
Mouse) is an international collaborative research project initiated and organized
by the RIKEN Omics Science Center in Yokohama, Japan. Previous work from the
FANTOM consortium has focused on identifying the transcribed components of mammalian
cells. FANTOM4 builds on this work, using novel methods to define how these
cellular components are regulated and work together as a biological network
in the acute myeloid leukemia cell line THP-1.

Among
the first FANTOM4 papers to be published in Genome
Biology
is a description of a suite of computer
programs
from Josee Dostie and colleagues which allow chromatin conformation
signatures to be identified. In the same journal, Alistair Forrest
and colleagues describe EdgeExpressDB,
a new database and associated tools for interpreting biological networks
and comparing large high-throughput expression datasets. Further
work
published in BMC
Bioinformatics
by John Quackenbush and colleagues outlines two
new data-driven normalization strategies for
high-throughput
real-time
quantitative
PCR data. Additional research articles in this
article series will be published over coming months.

The FANTOM4 papers, including three additional companion articles just published
in Nature Genetics, are put in context
by Phil Kapranov’s minireview,
which is also published in the latest issue of Genome Biology.

View the latest posts on the On Biology homepage

Comments

By commenting, you’re agreeing to follow our community guidelines.

Your email address will not be published. Required fields are marked *