Vascular Cell launches a new thematic series on the topic of “Macrophages and Angiogenesis”. This new area of angiogenic research looks at the interplay between tissue and tumor macrophages and the vessels they interact with. The first contributions to this series discuss 1) myeloid cells and the tumor microenvironment, 2) Wnts and angiogenic macrophages, and 3) macrophages and lymphatic vessels.