Posts by Claire Barnard

Vegetable extract as a potential new therapy for HER2 positive breast cancer

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Breast cancer is the most common cancer in the UK, affecting 46,000 women each year. HER2, a cell surface receptor belonging to the family of epidermal growth factor receptors, is over-expressed in 30% of breast cancer patients, and these “HER2 positive” patients respond well to HER2-targeted therapies.

New research published in BMC Medicine by Parul Gupta and Sanjay Srivastava from Texas Tech University shows that phenethyl isothiocyanate (PEITC), a compound present in cruciferous vegetables, is a promising new treatment for HER2 positive breast cancer.

Breast cancer patients over-expressing HER2 respond well to treatment with trastuzumab (Herceptin), a monoclonal antibody therapy targeting HER2. While this therapy is effective …

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