For almost thirty years, David Stern has been obsessed with the fact that male fruit flies ‘sing’ to females. His work on this problem, published today in BMC Biology, has got him thinking about reproducibility in science. In this guest post, he sets out his prescription to help scientists check whether research results are reliable
As an undergraduate at Cornell in 1985, I looked for a research problem that combined my interests in genetics, evolution, and behavior. Kyriacou and Hall had recently reported that the period gene, which regulates circadian rhythms, also controlled a rhythm of fruit fly courtship song and that evolution of period explained a species difference in this courtship song rhythm. This seemed …
Ever since seeing this amazing computer reconstruction of moas on David Attenborough’s Life of Birds, I’ve been slightly obsessed by them. These giant birds seem to have died out in around 1400, hunted to extinction by the Maori who arrived on the island about a century before. There have been the odd unsubstantiated report of sightings, but I do suspect if there were six foot tall carnivorous birds running around New Zealand, we’d probably know about it. Attenborough’s computer reconstruction seems to be the nearest we’re likely to get to get to seeing these creatures.
But that hasn’t stopped scientists from finding out as much as they can, from the few moa bones we have. A new study in …
Yesterday, Autism Awareness Month in the US drew to a close. To mark this, Dr Joseph Buxbaum and Dr Silvia De Rubeis of the Seaver Autism Center for Research and Treatment tell us about the condition and the exploration of the genetics behind it.
Autism spectrum disorder (often simply known as autism) describes a group of neurodevelopmental disorders that manifest with an array of disabilities. A person is diagnosed with autism when they have persistent deficits in social communication and social interaction, and restricted patterns of behavior, interests, or activities.
A recent report released from the Centers for Disease Control and Prevention (CDC) indicates that 1 in 68 children in the US suffer from autism, while …
To mark today’s launch of Canine Genetics and Epidemiology, we asked the Kennel Club’s Health Information Manager, Aimée Llewellyn, to tell us more about the journal’s background and its potential impact on the wellbeing of dogs:
The Kennel Club had been working to improve their educational resources for many years. In late 2011, it was agreed to investigate developing or potentially linking with a canine-focused scientific journal to make the newly emerging genetic research more accessible to the general public and dog breeders, as well as a more centralized resource for the veterinary community.
The problem was there wasn’t a journal already in place that focused purely, or even mainly, on dog health. So we looked into the …
The field of mobile DNA is currently a very exciting area of genetics and genomics research. It was once assumed that transposable elements were useless DNA sequences that incorporated into host genomes, forming ‘junk DNA’. In recent years, however, the significance of these genetic elements has been increasingly realized, with studies regularly being published hinting at the function of transposable elements in the host genome.
It seems that some of these suspected functions are damaging to the host, and others may even be beneficial; either way, the contribution of mobile elements to genome evolution is now a hugely interesting area, providing new insights into the evolutionary ‘arms race’ between organisms.
On March 9-14th, BioMed Central attended the Keystone meeting Mobile …
What have dogs ever done for us?
Humans and dogs have a long history of co-existence and companionship, and our four-legged friends can have a profound impact on our wellbeing in a number of ways.
The company of dogs has long been thought to reduce anxiety and improve health outcomes, to the extent that Florence Nightingale recommended small pets as “an excellent companion for the sick, for long chronic cases especially” (as Professor James Serpell reports).
Animal-human therapeutic interactions are now an established component of modern medical treatment: the Memorial Sloan Kettering Cancer Center has had a dedicated team of therapy dogs for cancer patients since 2007. Alongside this, guide and hearing dogs have been able to provide essential support …
This is a guest post by Sheila McCormick, an editor for BMC Plant Biology. To mark International Women’s Day, she takes a look back over her career in plant genetics and publishing.
When I started college at Illinois State University, I thought I might become a high school biology teacher. But as the semesters went on I started to consider going to graduate school. The professor who taught Genetics, Dr. Herman Brockman, was an inspiration – I basically fell in love with Genetics and decided to do a PhD.
I first started graduate school at Univ. Texas-Austin, intending to work on fruit fly genetics. As an undergraduate I had read a paper in the journal Genetics about the …
Analysis of 19th century harvest records from an isolated Swedish community reveals that female grandchildren have an increased risk of death from heart disease if their paternal grandmother experienced a drastic change in food availability in their childhood.
Staying stress free, keeping fit, eating well – these are all things we’re advised to do to keep our hearts healthy. But have you ever thought about whether what your parents and grandparents did could be affecting you too? New research has suggested that the diet experiences of even your grandparents could have an effect on your own health.
Food shortage and famine are clearly not good for you. Associations between higher risk of cardiovascular disease and stroke among adults who suffered famine …
The proceedings from the International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics have been published as a supplement in Molecular Cytogenetics. The meeting took place on the 22-25 January, 2014, in Ahmedabad, India.
Former President of India, Dr A. P. J. Abdul Kalam, inaugurated the conference, and can be seen handing the journal supplement to the Molecular Cytogenetics Co-Editor-in-Chief Thomas Liehr (Friedrich Schiller University, Jena, Germany).
From left: Prof. Jayesh Sheth (head of FRIGE’s Institute and organizer of this annual meeting); Hon’ble Former President of India Dr A P J Abdul Kalam; Mr. Akshay Saxena (Mission director, Gujarat State Biotech Mission); Prof. Alok Dhawan …
A recent study published in Investigative Genetics has shown that the genetic lineage of most Western Europeans started from just one to three men, sparking many and varied online discussions.
The study, led by Chris Tyler-Smith, involved producing a model to investigate the expansion of Neolithic genetic lineages throughout Africa and Europe. Both Africa and Western Europe have a predominant genetic lineage, or haplogroup, and genetic and archaeological evidence show that both of these haplogroups expanded in their respective populations during the Neolithic period (from about 10,000BC to 3000BC).
The haplogroups investigated in this study are variations of the Y chromosome, only present in men. Using advanced sequencing tools it was therefore possible to produce a model …