Posts tagged: Frontotemporal dementia

Dementia – a worry for younger people too


Frontotemporal dementia (FTD) is the second most common form of dementia that affects younger people and is the focus of a new thematic series from Alzheimer’s Research & Therapy and a forthcoming scientific conference.

It is reported that 15 to 20 of 100,000 individuals aged between 45 to 64 years, in Western countries, are affected; placing a large economic burden on society and indicating an international prevalence of the disease.

The genetic mutation responsible for FTD was identified in 2011, as a pathogenic expansion of the GGGGCC hexanucleotide repeat in the intron region of the chromosome 9 open reading frame 72 (C9ORF72) gene. The disease is known as FTD or amyotrophic lateral sclerosis (ALS) linked to chromosome 9 (c9FTD/ALS). …

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