Analysis of 19th century harvest records from an isolated Swedish community reveals that female grandchildren have an increased risk of death from heart disease if their paternal grandmother experienced a drastic change in food availability in their childhood.
Staying stress free, keeping fit, eating well – these are all things we’re advised to do to keep our hearts healthy. But have you ever thought about whether what your parents and grandparents did could be affecting you too? New research has suggested that the diet experiences of even your grandparents could have an effect on your own health.
Food shortage and famine are clearly not good for you. Associations between higher risk of cardiovascular disease and stroke among adults who suffered famine …
Epigenetics & Chromatin is inviting submissions for a thematic series on non-coding RNA, edited by Frank Grosveld (Erasmus University Medical Center, Netherlands) and Steven Henikoff (Fred Hutchinson Cancer Research Center, USA).
This article collection focuses on understanding the mechanisms of non-coding RNA, describing insights into the biogenesis and activity of non-coding RNAs, their interaction with chromatin, and novel methods for analysis and manipulation of RNA-mediated regulation.
The thematic series is open for the submission of Research articles on all aspects of non-coding RNA, including novel findings related to long-, short- and micro- RNAs. Articles already published in the series include an insight into the silencing mechanism by the long non-coding RNA XIST that …
To mark the BioMed Central conference Epigenetics & Chromatin: Interactions and processes that took place in Boston earlier this year, the open access journal Epigenetics & Chromatin has published a series of review articles that focus on addressing some of the biggest questions in epigenetics today.
The final review of the series, by Anton Wutz (ETH Zurich, Switzerland), has been published today, discussing how haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals. In this review the authors, who have significantly advanced our understanding of haploidy in mammals, provide an insightful summary of systems available to study haploid genomes.
Other reviews in the series include a description of the role of the …
Epigenetics could play an important role in the future of bird breeding and selection methods, according to a new review published in Genetics Selection Evolution today. There is hope that our increasing knowledge of epigenetic influence on development may help the future bird farming industry to meet the growing world food demand. Frésard et al. discuss the existing research into epigenetic mechanisms in birds, and how this may affect development of various economically relevant traits in adult farmed birds. Previous research has confirmed that many different epigenetic phenomena cause phenotypic variation in mammals, and we now learn that many of these mechanisms may also be relevant to birds.
Reciprocal effects, involving different contributions of the sire and dam …
BioMed Central will be hosting this inaugural conference in association with its journal Epigenetics & Chromatin at Harvard Medical School, Boston, USA, on the 11-13 March 2013.
The conference will have a strong focus on how epigenetic components come together to regulate cellular processes. “Epigenetics research is progressing from a listing of component parts to a fuller understanding of dynamic processes,” states Steven Henikoff (Fred Hutchinson Cancer Research Center), conference organizer and co-Editor-in-Chief of Epigenetics & Chromatin. Henikoff continues that “Many disease states are increasingly recognized as having both a genetic and an epigenetic basis, and chromatin regulators are often found to be cancer driver genes,”. This conference will highlight how the discovery of these epigenetic changes …