Evaluating cost effectiveness models of vaccine implementation

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Vaccinations, generally considered to be the most effective method for preventing infectious diseases, provide protection in terms of human cost, and may also provide good economic value. Cost effectiveness is an important factor for stakeholders in deciding whether to add an additional vaccine into the national vaccination program. Mathematical cost effectiveness models are useful in aiding decisions on whether or not to implement a new vaccination program. 

Raymond Hutubessy and colleagues from the World Health Organization (WHO) have today published a series of three articles for BMC Medicine that aim to make decision makers more aware of the intricacies of different types of cost effectiveness models, and to encourage modelers to share their expertise. In a debate …

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Sizing up Alzheimer’s disease

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Despite being the seventh leading cause of death in the United States and costing the country over $100 billion a year, there remain no proven disease-modifying therapies for Alzheimer’s disease (AD). Progress in translating our understanding of the disease into effective therapies is limited when compared, for example, with HIV/AIDS, the causative agents of which were discovered during a similar period in history to those of AD, and for which multiple anti-viral therapies developed over two decades have transformed a fatal disease into one that is more manageable, at least in industrialized nations.

An editorial published last week in Alzheimer’s Research & Therapy by two of its Editors-in-Chief, Todd Golde and Douglas Galasko, and their co-author Bruce Lamb, …

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Breaking down barriers with new Edanz partnership

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BioMed
Central has announced a new agreement with Edanz, a leading medical and
scientific editing service provider, to provide researchers with cost-effective
and comprehensive English language support throughout the peer review process.
As part of this agreement, BioMed Central authors will be eligible to receive a
discount on Edanz’s services.

This
agreement will significantly improve the publishing experience of BioMed
Central authors worldwide, allowing them to obtain English language assistance
wherever they need it.

Edanz’s
services are provided by expert scientists and will support authors through
manuscript submission, peer-review,addressing reviewers’ comments, as well as
assistance with writing cover letters and advising on the most appropriate
journal for their papers. In addition, Edanz will be providing free workshops
and …

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Virtual slides – an exciting new addition to Diagnostic Pathology articles

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Diagnostic Pathology, BioMed Central’s independent pathology journal, is now offering authors the option to include virtual versions of their figures alongside their articles. Traditionally, pathology figures rely on tissue staining, and reproducing these images faithfully in journal articles can be challenging, leading to some loss of resolution. Including virtual versions of these figures is a major step forward in pathology research publishing and will allow for greater analysis of the article figures.

Led by Editor-in-Chief Klaus Kayser, Diagnostic Pathology publishes research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The new addition of an option to publish virtual slides alongside the journal articles promises to move the …

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BioMed Central’s 5th Annual Research Awards, and the winners are…

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The winners of our 5th Annual Research Awards were announced last night at ZSL London Zoo, Regent’s Park, London, UK. Celebrating the very best research that has been made available by open access publishing, more than 120 guests attended the prestigious ceremony including leading researchers, shortlisted authors and science journalists from around the world. The winners were selected from 214 BioMed Central journals which published more than 17,000 peer-reviewed open access articles over the last 12 months. 

Congratulations to all our winners.

 

Biology Award, in association with Roche 

Roberto Danovaro, Polytechnic University of Marche, Italy

The first metazoa living in permanently anoxic conditionsBMC Biology 2010, 8:30 (6 April 2010)

Medicine Award

Christina Jones, University of Liverpool, UK

Intensive care diaries reduce …

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Battle of the sex chromosomes

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It’s something of a platitude that men and women want different things, but it seems that just such a battle is fought out on the sex chromosomes. Genes that are mainly expressed in only one of the sexes – for example, those that have important roles in the ovary or testis – are distributed unequally: even though the X chromosome is found in both sexes, it contains more female-biased than male-biased genes. A common explanation for this difference is that the mammalian X chromosome is inactivated early in spermatogenesis, making it a poor location for genes necessary for sperm production.

However, according to a new study in BMC Biology, this won’t work for Drosophila. Fruit fly X chromosomes don’t seem …

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A new Flavour of journal is cooking up a storm

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Enter Flavour’s exclusive competition for
your chance to win a free copy of
Peter Barham’s Science of Cooking

The recent explosion of
Molecular Gastronomy has brought the worlds of the laboratory and the kitchen
closer together with science playing an increasingly pivotal role in food and
cooking. BioMed Central’s new journal, Flavour,
will allow all stakeholders to read the latest and highest quality scientific
research in this field. Focussing on flavour generation and perception, and its
influence on behaviour and nutrition, Flavour is now accepting
submissions and will publish research relating to all contexts – whether it be
everyday cooking, haute cuisine or government policy on healthy eating.

Peter Barham (University of Bristol and author …

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Open access vital for safeguarding UK scholarly research

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A new commissioned report has recommended that
academic policymakers promote the adoption of gold-route open access publishing
to help increase access to scholarly journals.

Commissioned by Research Information Network (RIN), Research Libraries UK, the Wellcome Trust,
the Publishing Research Consortium and the Joint Information Systems Committee,
the report ‘Heading for the open road: costs and benefits of
transitions in scholarly communications’
is the result of a
wide-ranging consultation on the future of the scholarly publishing landscape
with UK-based stakeholders including research funders, librarians and
publishers.

The report, part of RIN’s Transitions in Scholarly Communication portfolio,
examines five different routes for achieving greater access to research
articles, and scrutinizes the relative costs and benefits of each method. Its
authors …

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Break out the bubbly – Medical Gas Research launches

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BioMed Central launches Medical Gas Research this week, a new open-access journal led by Editor-in-Chief John Zhang.

Medical gases are used in a variety of multidisciplinary fields of clinical practice such as diving medicine, anesthesiology, emergency medicine, hyperbaric oxygen medicine as well as basic science research fields including biochemistry and neuroscience. As Professor Zhang explains in his launch editorial, Medical Gas Research provides a platform encompassing all aspects of this research, from basic science to the clinical applications of medical gas research, with particular focus on the neurobiological effects of related disorders.

Among the other articles published at launch include original research by Dong et al. on the role of the anesthetic component isoflurane and …

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Popular books about sex differences

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The topic of the differences in male and female’s brains and behaviour has triggered a succession of popular books over the last decade which has helped advance study into the area of human brain differences in relation to sex and gender. In a book review, published today in Biology of Sex Differences, authors Margaret  McCarthy and Gregory  Ball provide a critique of two recent publications, Rebecca J. Jordan-Young’s “Brainstorm: The Flaws in the Science of Sex Differences” and Cordelia Fine’s “Delusions of Gender"                                                                 
The critics agree with aspects of both Jordan-Young’s and  Fine’s approaches to questioning the translation of research in this field, but point out that there are areas of research that have …

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