In an editorial on the debate surrounding the role and abundance of “dark matter” RNA, BMC Biology concluded that we need to know more about the function of specific non-coding RNAs before we can make more general judgments about their role.
So what do we know about ncRNA function so far? Quite a lot – but only about a few of them. Known functional ncRNAs, and the diversity of methods by which they might act, are well-covered by Chris Ponting in a 2009 review. But those dark matter RNAs for which we have a known function and mechanism are hugely outnumbered by those for which we don’t, with less than 100 being well-characterized so far. There are significantly more …
Disruptions to thyroid hormone synthesis and action is one of the most common endocrine disorders. The actions of thyroid hormones are crucial to most body systems, hence the effects of thyroid disorders are felt with varying degrees of severity.
Thyroid Research has recently published its first supplement, ‘New aspects of thyroid hormone synthesis and action’, discussing the most recent developments in the understanding of thyroid hormone action and how this could assist improvements in the diagnosis and treatment of thyroid disorders. Lead by guest editor Dr Heike Biebermann, the supplement includes some of the latest research into RNA-binding proteins, transporters, thyroid hormone action and synthesis, and the potential …
Neural Systems & Circuits is publishing a special thematic series dedicated to advances in invertebrate circuitry research. The series intends to provide the reader with an overview of new and exciting developments in the field, and will publish reviews and research from key scientists working on diverse model organisms, using either computational or experimental approaches.
For more information on the series, and an introduction to the work featured, please see the recently published Editorial written by Prof. George Kemenes. The first review, published by Prof. Malcolm Burrows, concentrates on the circuitry of phase change in the locust. Further contributions on …
Genome Biology’s recent waltz around the 19th Annual Conference on Intelligent Systems in Molecular Biology (ISMB) in Vienna gave us a quickstep tour around the current developments in the computational biology community, including advances in the fields of personalized medicine and the genomic “data deluge”.
It also highlighted the acute awareness that computational biologists have of the importance of sharing data.
The International Society for Computational Biology (ISCB), who organized the conference, are stepping up and taking the lead when it comes to endorsing the free availability of data and open access to research—a theme that was heavily present among this year’s speakers. In a compelling announcement published last year, the society released the following public policy …
Harm Reduction Journal has
recently affiliated with Harm Reduction
International (HRI), formerly known as the International Harm Reduction
Association, one of the
leading international non-governmental organizations working
in harm reduction and drug policy reform.
Together, Harm Reduction Journal and HRI aim to reduce
drug related harms by promoting evidence-based public health policies and
programs to reduce the
adverse medical, economic, public health, and social consequences associated
with both drugs and drug policies.
Ernest Drucker, Editor-in-Chief of Harm Reduction Journal and an
internationally recognized public health scholar explains the importance of
this new partnership:
"The affiliation of Harm Reduction Journal with Harm Reduction International (HRI)
marks an important milestone in the evolution of our journal. With its 1500 members worldwide and
important regional programs, HRI …
Stem Cell Research & Therapy is expected to receive its first Impact Factor in June 2012, having been accepted for tracking by Thomson Reuters (ISI). The journal launched in March 2010 and recently marked its first anniversary. Congratulations to Rocky Tuan and Timothy O’Brien, the Editors-in-Chief, and the Editorial Board for ensuring such a strong start for the journal, as indicated by the fact it will be indexed from Volume 1.
In addition to outstanding open access research articles with a focus on stem cell therapeutics, such as a recent article from Deborah Sullivan’s group investigating how human multipotent stromal cells attenuate inflammation in acute lung injury, Stem Cell Research & Therapy also …
Dr Constantine Vardavas has recently joined Tobacco Induced Diseases, the official journal of the International Society for the Prevention of Tobacco Induced Diseases as co-Editor-in-Chief alongside Dr James Elliott Scott.
Constantine Vardavas is with the Center for Global Tobacco Control at the Harvard School of Public Health. Throughout his academic and professional career, Dr Vardavas’ research has focused on the health effects of smoking and secondhand smoke exposure, particularly during childhood and pregnancy, and on tobacco prevention and policy.
In addition, Dr Vardavas has a special interest in efforts to reduce the smoking epidemic affecting Greece and is currently serving as the project director of HEART (Hellenic Action for Research Against Tobacco), a project aimed to apply gold standard tobacco control measures within the Hellenic Region as a …
Longevity & Healthspan is an exciting new interdisciplinary open access journal focused on the biology of aging in the context of age-related disease and healthy lifespan. The journal emphasizes advancing our understanding of how age-related changes in structure and function become risk factors for or accompany age-related diseases or conditions, and the biology underlying healthy aging and longevity.
Aging represents the most important risk factor for chronic disease and frailty, with the many age-related conditions including cancer, cardiovascular disease, metabolic disease and type 2 diabetes, neurodegenerative disease, osteoporosis, and decreased immune function.
The journal is jointly overseen by Editors-in-Chief James Kirkland (Mayo Clinic, USA), Gordon …
With major depression being one of the leading causes of disability worldwide, impacting on many different areas of life, including pregnancy and work absence, treatment and management of this debilitating condition garners a lot of attention. However, from a public health perspective, better understanding the patterns and causes of depression will help guide initiatives to reduce the impact of depression on individuals and society.
In a new research article published this week in BMC Medicine, Bromet and colleagues from around the world present the results of their multi-national study looking at the epidemiology of major depressive episode from 18 countries (including low/medium and high income nations), reporting on prevalence, impairment and demographic aspects. Although they …
Clinical Sarcoma Research (CSR) has launched with BioMed Central. CSR publishes the latest advances on rare solid cancers – sarcomas – and aims to be a platform for the sharing and discussion of clinical knowledge within this field.
Editors-in-Chief, Paola Casali and Angelo Dei Tos highlight networking as vital for dealing with rare cancers, and therefore the journal encourages clinicians and researchers to share their first-hand medical experiences and translational research with the global sarcoma community. It is also hoped that guidelines for better diagnosis, treatment and patient care can be developed through the sharing of clinical and translational research.
In clinical sarcoma …